DegronMD: protein-targeted degradation, mutation and drug response to degrons
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BSML
CPH
CGC
Degron:
HKENQ
Uniprot ID:
Q8TAB7
Source protein:
Putative coiled-coil domain-containing protein 26
Source gene:
CCDC26
Class:
DEG_APCC_KENBOX_2
Location:
84:88
E3 ligase:
APC,CDC20,FZR1
DEGRON score:
0.7306
ASA_SCORE:
107.32
COIL:
0.7216
CONS_SCORE:
0
DSS_SCORE:
0.5413
HELIX:
0.2304
FCONS_SCORE:
0
RIG_SCORE:
0.7126
Degron related mutations and impact score
Mutation
Sample
Cancer
Dataset
Degron
Degron class
Impact score
Drug responses associated with CCDC26 mutations
Sample
Cancer
Mutation (In Degron?)
Dataset
Drug
IC50
All proteins holding degron of HKENQ
Uniprot ID
Source protein
Degron class
Location
Hit
E3 ligase
Degron score
Detail
Q8TAB7
Putative coiled-coil domain-containing protein 26
DEG_APCC_KENBOX_2
84:88
HKENQ
APC,CDC20,FZR1
0.7306
More...