DegronMD: protein-targeted degradation, mutation and drug response to degrons
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Degron:
HRPNLSGIP
Uniprot ID:
Q8NDB6
Source protein:
Protein FAM156A/FAM156B
Source gene:
FAM156A; FAM156B
Class:
DEG_APCC_DBOX_1
Location:
134:142
E3 ligase:
APC,CDC20,FZR1
DEGRON score:
0.9083
ASA_SCORE:
71.7222
COIL:
0.8863
CONS_SCORE:
0.693
DSS_SCORE:
0.4231
HELIX:
0.0663
FCONS_SCORE:
1.028
RIG_SCORE:
0.638
Degron related mutations and impact score
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Drug responses associated with FAM156A; FAM156B mutations
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All proteins holding degron of HRPNLSGIP
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Uniprot ID
Source protein
Degron class
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E3 ligase
Degron score
Detail
Q8NDB6
Protein FAM156A/FAM156B
DEG_APCC_DBOX_1
134:142
HRPNLSGIP
APC,CDC20,FZR1
0.9083
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