DegronMD: protein-targeted degradation, mutation and drug response to degrons
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BSML
CPH
CGC
Degron:
IFTPAHE
Uniprot ID:
C9JLW8
Source protein:
Mapk-regulated corepressor-interacting protein 1
Source gene:
MCRIP1
Class:
DEG_SCF_FBW7_2
Location:
28:34
E3 ligase:
FBXW7
DEGRON score:
0.9916
ASA_SCORE:
69.2286
COIL:
0.5501
CONS_SCORE:
0.9549
DSS_SCORE:
0.4542
HELIX:
0.4159
FCONS_SCORE:
1.1708
RIG_SCORE:
0.7213
Degron related mutations and impact score
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Drug responses associated with MCRIP1 mutations
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All proteins holding degron of IFTPAHE
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Uniprot ID
Source protein
Degron class
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Hit
E3 ligase
Degron score
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C9JLW8
Mapk-regulated corepressor-interacting protein 1
DEG_SCF_FBW7_2
28:34
IFTPAHE
FBXW7
0.9916
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