DegronMD

Uniprot ID: O96028

Source protein: Histone-lysine N-methyltransferase NSD2

Source gene: NSD2

Class: DEG_SCF_FBW7_1

Location: 108:114

E3 ligase: FBXW7

DEGRON score: 0.993

ASA_SCORE: 81.4857

COIL: 0.947

CONS_SCORE: 0.3188

DSS_SCORE: 0.6696

HELIX: 0.0169

FCONS_SCORE: 0.9831

RIG_SCORE: 0.6267

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.L109I	NCI-H1355	lung	COSMIC	IGTPPNT	DEG_SCF_FBW7_1	0.7174

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
O96028	Histone-lysine N-methyltransferase NSD2	DEG_SCF_FBW7_1	108:114	IGTPPNT	FBXW7	0.993	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons