DegronMD

Uniprot ID: P17028

Source protein: Zinc finger protein 24

Source gene: ZNF24

Class: DEG_SCF_FBW7_2

Location: 13:20

E3 ligase: FBXW7

DEGRON score: 0.9834

ASA_SCORE: 94.25

COIL: 0.8446

CONS_SCORE: 0.3648

DSS_SCORE: 0.5196

HELIX: 0.1338

FCONS_SCORE: 0.8256

RIG_SCORE: 0.757

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.P17Q	TCGA-37-3789	LUSC	TCGA	IIPTPDEE	DEG_SCF_FBW7_2	0.7035
p.P17Q	DO26743	LUSC	ICGC	IIPTPDEE	DEG_SCF_FBW7_2	0.7035
p.T16N	SIDM00845	Burkitt's Lymphoma	GDSC	IIPTPDEE	DEG_SCF_FBW7_2	0.8166
p.T16N	SIDM00461	Acute Myeloid Leukemia	GDSC	IIPTPDEE	DEG_SCF_FBW7_2	0.8166

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
P17028	Zinc finger protein 24	DEG_SCF_FBW7_2	13:20	IIPTPDEE	FBXW7	0.9834	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons