DegronMD

Uniprot ID: Q9H706

Source protein: GRB2-associated and regulator of MAPK protein 1

Source gene: GAREM1

Class: LIG_APCC_ABBA_1

Location: 420:425

E3 ligase: APC,CDC20,FZR1

DEGRON score: 0.8957

ASA_SCORE: 82.6667

COIL: 0.8822

CONS_SCORE: 0.1783

DSS_SCORE: 0.4883

HELIX: 0.0472

FCONS_SCORE: 0.7034

RIG_SCORE: 0.7492

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.P417S	SIDM01692	T-Cell Non-Hodgkin's Lymphoma	GDSC	ILPYQD	LIG_APCC_ABBA_1	0.25

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q9H706	GRB2-associated and regulator of MAPK protein 1	LIG_APCC_ABBA_1	420:425	ILPYQD	APC,CDC20,FZR1	0.8957	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons