DegronMD: protein-targeted degradation, mutation and drug response to degrons
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Degron:
IPLYEE
Uniprot ID:
Q86YA3
Source protein:
Protein ZGRF1
Source gene:
ZGRF1
Class:
LIG_APCC_ABBA_1
Location:
1422:1427
E3 ligase:
APC,CDC20,FZR1
DEGRON score:
0.558
ASA_SCORE:
47.6333
COIL:
0.5562
CONS_SCORE:
0
DSS_SCORE:
0.0509
HELIX:
0.0028
FCONS_SCORE:
0
RIG_SCORE:
0.8968
Degron related mutations and impact score
Mutation
Sample
Cancer
Dataset
Degron
Degron class
Impact score
Drug responses associated with ZGRF1 mutations
Sample
Cancer
Mutation (In Degron?)
Dataset
Drug
IC50
All proteins holding degron of IPLYEE
Uniprot ID
Source protein
Degron class
Location
Hit
E3 ligase
Degron score
Detail
Q86YA3
Protein ZGRF1
LIG_APCC_ABBA_1
1422:1427
IPLYEE
APC,CDC20,FZR1
0.558
More...