DegronMD: protein-targeted degradation, mutation and drug response to degrons
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Degron:
IPPFGE
Uniprot ID:
A8MT66
Source protein:
Putative uncharacterized protein ENSP00000383407
Source gene:
-
Class:
LIG_APCC_ABBA_1
Location:
37:42
E3 ligase:
APC,CDC20,FZR1
DEGRON score:
0.9012
ASA_SCORE:
72.9667
COIL:
0.8827
CONS_SCORE:
0
DSS_SCORE:
0.7374
HELIX:
0.0683
FCONS_SCORE:
0
RIG_SCORE:
0.5944
Degron related mutations and impact score
Mutation
Sample
Cancer
Dataset
Degron
Degron class
Impact score
Drug responses associated with - mutations
Sample
Cancer
Mutation (In Degron?)
Dataset
Drug
IC50
All proteins holding degron of IPPFGE
Uniprot ID
Source protein
Degron class
Location
Hit
E3 ligase
Degron score
Detail
A8MT66
Putative uncharacterized protein ENSP00000383407
LIG_APCC_ABBA_1
37:42
IPPFGE
APC,CDC20,FZR1
0.9012
More...