DegronMD: protein-targeted degradation, mutation and drug response to degrons
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Degron:
IPTPVPT
Uniprot ID:
P59797
Source protein:
Selenoprotein V
Source gene:
SELENOV
Class:
DEG_SCF_FBW7_1
Location:
93:99
E3 ligase:
FBXW7
DEGRON score:
0.9055
ASA_SCORE:
93.2571
COIL:
0.968
CONS_SCORE:
0.5576
DSS_SCORE:
0.3943
HELIX:
0.0059
FCONS_SCORE:
0.9614
RIG_SCORE:
0.6721
Degron related mutations and impact score
Mutation
Sample
Cancer
Dataset
Degron
Degron class
Impact score
Drug responses associated with SELENOV mutations
Sample
Cancer
Mutation (In Degron?)
Dataset
Drug
IC50
All proteins holding degron of IPTPVPT
Uniprot ID
Source protein
Degron class
Location
Hit
E3 ligase
Degron score
Detail
P59797
Selenoprotein V
DEG_SCF_FBW7_1
93:99
IPTPVPT
FBXW7
0.9055
More...