DegronMD

Uniprot ID: Q6UWH4

Source protein: Golgi-associated kinase 1B

Source gene: GASK1B

Class: LIG_APCC_ABBA_1

Location: 205:210

E3 ligase: APC,CDC20,FZR1

DEGRON score: 0.9839

ASA_SCORE: 69.3167

COIL: 0.6368

CONS_SCORE: 0.8245

DSS_SCORE: 0.3679

HELIX: 0.0583

FCONS_SCORE: 1.3503

RIG_SCORE: 0.7553

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.A212T	SIDM02041	Colorectal Carcinoma	GDSC	IRIYSE	LIG_APCC_ABBA_1	0.2778
p.A212T	SIDM00114	Non-Small Cell Lung Carcinoma	GDSC	IRIYSE	LIG_APCC_ABBA_1	0.2778
p.A212T	H513	pleura	COSMIC	IRIYSE	LIG_APCC_ABBA_1	0.2778

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q6UWH4	Golgi-associated kinase 1B	LIG_APCC_ABBA_1	205:210	IRIYSE	APC,CDC20,FZR1	0.9839	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons