DegronMD: protein-targeted degradation, mutation and drug response to degrons
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BSML
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Degron:
ISTPVQT
Uniprot ID:
Q2M2H8
Source protein:
Probable maltase-glucoamylase 2
Source gene:
MGAM2
Class:
DEG_SCF_FBW7_1
Location:
2141:2147
E3 ligase:
FBXW7
DEGRON score:
0.9704
ASA_SCORE:
85.8714
COIL:
0.8844
CONS_SCORE:
0
DSS_SCORE:
0.4707
HELIX:
0.0163
FCONS_SCORE:
0
RIG_SCORE:
0.764
Degron related mutations and impact score
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Drug responses associated with MGAM2 mutations
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All proteins holding degron of ISTPVQT
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Uniprot ID
Source protein
Degron class
Location
Hit
E3 ligase
Degron score
Detail
Q2M2H8
Probable maltase-glucoamylase 2
DEG_SCF_FBW7_1
2141:2147
ISTPVQT
FBXW7
0.9704
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