DegronMD: protein-targeted degradation, mutation and drug response to degrons
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Degron:
KHNLYRD
Uniprot ID:
Q96TA1
Source protein:
Protein Niban 2
Source gene:
NIBAN2
Class:
LIG_APCC_ABBAyCdc20_2
Location:
561:567
E3 ligase:
APC,CDC20,FZR1
DEGRON score:
0.9702
ASA_SCORE:
92.9714
COIL:
0.557
CONS_SCORE:
0.4565
DSS_SCORE:
0.3249
HELIX:
0.3683
FCONS_SCORE:
1.0023
RIG_SCORE:
0.7898
Degron related mutations and impact score
Mutation
Sample
Cancer
Dataset
Degron
Degron class
Impact score
Drug responses associated with NIBAN2 mutations
Sample
Cancer
Mutation (In Degron?)
Dataset
Drug
IC50
All proteins holding degron of KHNLYRD
Uniprot ID
Source protein
Degron class
Location
Hit
E3 ligase
Degron score
Detail
Q96TA1
Protein Niban 2
LIG_APCC_ABBAyCdc20_2
561:567
KHNLYRD
APC,CDC20,FZR1
0.9702
More...