DegronMD: protein-targeted degradation, mutation and drug response to degrons
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BSML
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Degron:
KPVLFGE
Uniprot ID:
Q6ZUG5
Source protein:
Uncharacterized protein FLJ43738
Source gene:
-
Class:
LIG_APCC_ABBAyCdc20_2
Location:
70:76
E3 ligase:
APC,CDC20,FZR1
DEGRON score:
0.991
ASA_SCORE:
73.2571
COIL:
0.7571
CONS_SCORE:
0.2795
DSS_SCORE:
0.4894
HELIX:
0.0607
FCONS_SCORE:
0.7783
RIG_SCORE:
0.7463
Degron related mutations and impact score
Mutation
Sample
Cancer
Dataset
Degron
Degron class
Impact score
Drug responses associated with - mutations
Sample
Cancer
Mutation (In Degron?)
Dataset
Drug
IC50
All proteins holding degron of KPVLFGE
Uniprot ID
Source protein
Degron class
Location
Hit
E3 ligase
Degron score
Detail
Q6ZUG5
Uncharacterized protein FLJ43738
LIG_APCC_ABBAyCdc20_2
70:76
KPVLFGE
APC,CDC20,FZR1
0.991
More...