DegronMD: protein-targeted degradation, mutation and drug response to degrons
Home
(current)
Browse
Proteins/Degrons
Mutations
Drug response
Network-rewiring
Drug resistance
Search
Tutorial
Download
Contact
Links
BSML
CPH
CGC
Degron:
KRPRLDPIL
Uniprot ID:
A8MX19
Source protein:
Putative protein FAM90A12P
Source gene:
FAM90A12P
Class:
DEG_APCC_DBOX_1
Location:
157:165
E3 ligase:
APC,CDC20,FZR1
DEGRON score:
0.9154
ASA_SCORE:
99.1333
COIL:
0.8207
CONS_SCORE:
0.3279
DSS_SCORE:
0.573
HELIX:
0.1464
FCONS_SCORE:
0.8519
RIG_SCORE:
0.7231
Degron related mutations and impact score
Mutation
Sample
Cancer
Dataset
Degron
Degron class
Impact score
Drug responses associated with FAM90A12P mutations
Sample
Cancer
Mutation (In Degron?)
Dataset
Drug
IC50
All proteins holding degron of KRPRLDPIL
Uniprot ID
Source protein
Degron class
Location
Hit
E3 ligase
Degron score
Detail
A8MX19
Putative protein FAM90A12P
DEG_APCC_DBOX_1
157:165
KRPRLDPIL
APC,CDC20,FZR1
0.9154
More...