DegronMD: protein-targeted degradation, mutation and drug response to degrons
Home
(current)
Browse
Proteins/Degrons
Mutations
Drug response
Network-rewiring
Drug resistance
Search
Tutorial
Download
Contact
Links
BSML
CPH
CGC
Degron:
KRSVLGPVS
Uniprot ID:
A6NNH2
Source protein:
Protein FAM90A27P
Source gene:
FAM90A27P
Class:
DEG_APCC_DBOX_1
Location:
157:165
E3 ligase:
APC,CDC20,FZR1
DEGRON score:
0.9821
ASA_SCORE:
97.5556
COIL:
0.9411
CONS_SCORE:
0.2791
DSS_SCORE:
0.613
HELIX:
0.0162
FCONS_SCORE:
1.1601
RIG_SCORE:
0.6438
Degron related mutations and impact score
Mutation
Sample
Cancer
Dataset
Degron
Degron class
Impact score
Drug responses associated with FAM90A27P mutations
Sample
Cancer
Mutation (In Degron?)
Dataset
Drug
IC50
All proteins holding degron of KRSVLGPVS
Uniprot ID
Source protein
Degron class
Location
Hit
E3 ligase
Degron score
Detail
A6NNH2
Protein FAM90A27P
DEG_APCC_DBOX_1
157:165
KRSVLGPVS
APC,CDC20,FZR1
0.9821
More...