DegronMD

Uniprot ID: Q9BR76

Source protein: Coronin-1B

Source gene: CORO1B

Class: LIG_APCC_ABBAyCdc20_2

Location: 355:361

E3 ligase: APC,CDC20,FZR1

DEGRON score: 0.6729

ASA_SCORE: 58.2143

COIL: 0.6537

CONS_SCORE: 0.6949

DSS_SCORE: 0.3683

HELIX: 0.1967

FCONS_SCORE: 1.0818

RIG_SCORE: 0.7993

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.T351N	DO228978	LICA	ICGC	KSDLFQD	LIG_APCC_ABBAyCdc20_2	0.2222
p.P353T	DO229031	LICA	ICGC	KSDLFQD	LIG_APCC_ABBAyCdc20_2	0.2778
p.D366N	ACH-001403	Ovarian Cancer	CCLE	KSDLFQD	LIG_APCC_ABBAyCdc20_2	0.1944

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q9BR76	Coronin-1B	LIG_APCC_ABBAyCdc20_2	355:361	KSDLFQD	APC,CDC20,FZR1	0.6729	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons