DegronMD

Uniprot ID: O14514

Source protein: Adhesion G protein-coupled receptor B1

Source gene: ADGRB1

Class: LIG_APCC_ABBAyCdc20_2

Location: 1364:1370

E3 ligase: APC,CDC20,FZR1

DEGRON score: 0.7011

ASA_SCORE: 84.2714

COIL: 0.7283

CONS_SCORE: 0.359

DSS_SCORE: 0.6439

HELIX: 0.0974

FCONS_SCORE: 0.9793

RIG_SCORE: 0.7634

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.R1356Q	SIDM01301	Esophageal Carcinoma	GDSC	KYSIHID	LIG_APCC_ABBAyCdc20_2	0.1111

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
O14514	Adhesion G protein-coupled receptor B1	LIG_APCC_ABBAyCdc20_2	1364:1370	KYSIHID	APC,CDC20,FZR1	0.7011	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons