DegronMD: protein-targeted degradation, mutation and drug response to degrons
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Degron:
LAPAVAPGSLPL
Uniprot ID:
Q86XN8
Source protein:
RNA-binding protein MEX3D
Source gene:
MEX3D
Class:
DEG_ODPH_VHL_1
Location:
115:126
E3 ligase:
VHL
DEGRON score:
0.9926
ASA_SCORE:
69.7417
COIL:
0.857
CONS_SCORE:
0.2487
DSS_SCORE:
0.6708
HELIX:
0.0677
FCONS_SCORE:
1.0617
RIG_SCORE:
0.6032
Degron related mutations and impact score
Mutation
Sample
Cancer
Dataset
Degron
Degron class
Impact score
Drug responses associated with MEX3D mutations
Sample
Cancer
Mutation (In Degron?)
Dataset
Drug
IC50
All proteins holding degron of LAPAVAPGSLPL
Uniprot ID
Source protein
Degron class
Location
Hit
E3 ligase
Degron score
Detail
Q86XN8
RNA-binding protein MEX3D
DEG_ODPH_VHL_1
115:126
LAPAVAPGSLPL
VHL
0.9926
More...