DegronMD

Uniprot ID: Q16670

Source protein: Zinc finger and SCAN domain-containing protein 26

Source gene: ZSCAN26

Class: DEG_ODPH_VHL_1

Location: 11:23

E3 ligase: VHL

DEGRON score: 0.8934

ASA_SCORE: 88.6462

COIL: 0.7041

CONS_SCORE: 0.5065

DSS_SCORE: 0.2313

HELIX: 0.1226

FCONS_SCORE: 1.4209

RIG_SCORE: 0.7746

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.N15S	SIDM01117	Small Cell Lung Carcinoma	GDSC	LAPLNLKKEGLRV	DEG_ODPH_VHL_1	0.5958
p.N15S	SIDM00544	Neuroblastoma	GDSC	LAPLNLKKEGLRV	DEG_ODPH_VHL_1	0.5958
p.N15S	SIDM00493	Other Solid Cancers	GDSC	LAPLNLKKEGLRV	DEG_ODPH_VHL_1	0.5958
p.N15S	SIDM00397	Acute Myeloid Leukemia	GDSC	LAPLNLKKEGLRV	DEG_ODPH_VHL_1	0.5958
p.N15S	SIDM01033	Bladder Carcinoma	GDSC	LAPLNLKKEGLRV	DEG_ODPH_VHL_1	0.5958
p.N15S	SIDM00303	Ovarian Carcinoma	GDSC	LAPLNLKKEGLRV	DEG_ODPH_VHL_1	0.5958

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q16670	Zinc finger and SCAN domain-containing protein 26	DEG_ODPH_VHL_1	11:23	LAPLNLKKEGLRV	VHL	0.8934	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons