DegronMD: protein-targeted degradation, mutation and drug response to degrons
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BSML
CPH
CGC
Degron:
LDLYPE
Uniprot ID:
Q86X59
Source protein:
Putative uncharacterized protein LINC02875
Source gene:
LINC02875
Class:
LIG_APCC_ABBA_1
Location:
13:18
E3 ligase:
APC,CDC20,FZR1
DEGRON score:
0.7353
ASA_SCORE:
80.4333
COIL:
0.7423
CONS_SCORE:
0
DSS_SCORE:
0.5017
HELIX:
0.2065
FCONS_SCORE:
0
RIG_SCORE:
0.7692
Degron related mutations and impact score
Mutation
Sample
Cancer
Dataset
Degron
Degron class
Impact score
Drug responses associated with LINC02875 mutations
Sample
Cancer
Mutation (In Degron?)
Dataset
Drug
IC50
All proteins holding degron of LDLYPE
Uniprot ID
Source protein
Degron class
Location
Hit
E3 ligase
Degron score
Detail
Q86X59
Putative uncharacterized protein LINC02875
LIG_APCC_ABBA_1
13:18
LDLYPE
APC,CDC20,FZR1
0.7353
More...