DegronMD

Uniprot ID: Q5VU97

Source protein: VWFA and cache domain-containing protein 1

Source gene: CACHD1

Class: DEG_SCF_FBW7_1

Location: 1231:1237

E3 ligase: FBXW7

DEGRON score: 0.9962

ASA_SCORE: 85.6143

COIL: 0.8497

CONS_SCORE: 0.4153

DSS_SCORE: 0.5806

HELIX: 0.1291

FCONS_SCORE: 1.2506

RIG_SCORE: 0.7118

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.A1221S	DO229042	LICA	ICGC	LDTPPQT	DEG_SCF_FBW7_1	0.0556

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q5VU97	VWFA and cache domain-containing protein 1	DEG_SCF_FBW7_1	1231:1237	LDTPPQT	FBXW7	0.9962	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons