DegronMD: protein-targeted degradation, mutation and drug response to degrons
Home
(current)
Browse
Proteins/Degrons
Mutations
Drug response
Network-rewiring
Drug resistance
Search
Tutorial
Download
Contact
Links
BSML
CPH
CGC
Degron:
LEIYKE
Uniprot ID:
B7ZC32
Source protein:
Kinesin-like protein KIF28P
Source gene:
KIF28P
Class:
LIG_APCC_ABBA_1
Location:
158:163
E3 ligase:
APC,CDC20,FZR1
DEGRON score:
0.5485
ASA_SCORE:
42.7667
COIL:
0.3678
CONS_SCORE:
0.8665
DSS_SCORE:
0.0792
HELIX:
0.0718
FCONS_SCORE:
1.5863
RIG_SCORE:
0.9113
Degron related mutations and impact score
Mutation
Sample
Cancer
Dataset
Degron
Degron class
Impact score
Drug responses associated with KIF28P mutations
Sample
Cancer
Mutation (In Degron?)
Dataset
Drug
IC50
All proteins holding degron of LEIYKE
Uniprot ID
Source protein
Degron class
Location
Hit
E3 ligase
Degron score
Detail
B7ZC32
Kinesin-like protein KIF28P
LIG_APCC_ABBA_1
158:163
LEIYKE
APC,CDC20,FZR1
0.5485
More...