DegronMD

Uniprot ID: Q96GQ5

Source protein: RUS family member 1

Source gene: RUSF1

Class: DEG_SCF_FBW7_1

Location: 7:13

E3 ligase: FBXW7

DEGRON score: 0.8272

ASA_SCORE: 59.2

COIL: 0.5976

CONS_SCORE: 0.2806

DSS_SCORE: 0.5201

HELIX: 0.0116

FCONS_SCORE: 0.875

RIG_SCORE: 0.7618

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.E20K	SIDM00454	Rhabdomyosarcoma	GDSC	LETPLCS	DEG_SCF_FBW7_1	0.1389
p.E20K	SIDM01112	Osteosarcoma	GDSC	LETPLCS	DEG_SCF_FBW7_1	0.1389
p.E20K	SIDM00721	Small Cell Lung Carcinoma	GDSC	LETPLCS	DEG_SCF_FBW7_1	0.1389

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q96GQ5	RUS family member 1	DEG_SCF_FBW7_1	7:13	LETPLCS	FBXW7	0.8272	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons