DegronMD: protein-targeted degradation, mutation and drug response to degrons
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Degron:
LHLHPE
Uniprot ID:
Q8N6C7
Source protein:
Putative uncharacterized protein encoded by MIR7-3HG
Source gene:
MIR7-3HG
Class:
LIG_APCC_ABBA_1
Location:
88:93
E3 ligase:
APC,CDC20,FZR1
DEGRON score:
0.6256
ASA_SCORE:
72.5333
COIL:
0.8112
CONS_SCORE:
0
DSS_SCORE:
0.2716
HELIX:
0.0737
FCONS_SCORE:
0
RIG_SCORE:
0.7158
Degron related mutations and impact score
Mutation
Sample
Cancer
Dataset
Degron
Degron class
Impact score
Drug responses associated with MIR7-3HG mutations
Sample
Cancer
Mutation (In Degron?)
Dataset
Drug
IC50
All proteins holding degron of LHLHPE
Uniprot ID
Source protein
Degron class
Location
Hit
E3 ligase
Degron score
Detail
Q8N6C7
Putative uncharacterized protein encoded by MIR7-3HG
LIG_APCC_ABBA_1
88:93
LHLHPE
APC,CDC20,FZR1
0.6256
More...