DegronMD: protein-targeted degradation, mutation and drug response to degrons
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BSML
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Degron:
LKENW
Uniprot ID:
Q9H2J1
Source protein:
Uncharacterized protein ARRDC1-AS1
Source gene:
ARRDC1-AS1
Class:
DEG_APCC_KENBOX_2
Location:
59:63
E3 ligase:
APC,CDC20,FZR1
DEGRON score:
0.8258
ASA_SCORE:
49.6
COIL:
0.468
CONS_SCORE:
1
DSS_SCORE:
0.5978
HELIX:
0.246
FCONS_SCORE:
1.1
RIG_SCORE:
0.698
Degron related mutations and impact score
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Drug responses associated with ARRDC1-AS1 mutations
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All proteins holding degron of LKENW
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Uniprot ID
Source protein
Degron class
Location
Hit
E3 ligase
Degron score
Detail
Q9H2J1
Uncharacterized protein ARRDC1-AS1
DEG_APCC_KENBOX_2
59:63
LKENW
APC,CDC20,FZR1
0.8258
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