DegronMD: protein-targeted degradation, mutation and drug response to degrons
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Degron:
LNVHGE
Uniprot ID:
A6NJ88
Source protein:
Putative SAGE1-like protein
Source gene:
SAGE2P
Class:
LIG_APCC_ABBA_1
Location:
259:264
E3 ligase:
APC,CDC20,FZR1
DEGRON score:
0.5922
ASA_SCORE:
65.4667
COIL:
0.5228
CONS_SCORE:
0
DSS_SCORE:
0.4031
HELIX:
0.0467
FCONS_SCORE:
0
RIG_SCORE:
0.7669
Degron related mutations and impact score
Mutation
Sample
Cancer
Dataset
Degron
Degron class
Impact score
Drug responses associated with SAGE2P mutations
Sample
Cancer
Mutation (In Degron?)
Dataset
Drug
IC50
All proteins holding degron of LNVHGE
Uniprot ID
Source protein
Degron class
Location
Hit
E3 ligase
Degron score
Detail
A6NJ88
Putative SAGE1-like protein
LIG_APCC_ABBA_1
259:264
LNVHGE
APC,CDC20,FZR1
0.5922
More...