DegronMD: protein-targeted degradation, mutation and drug response to degrons
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Degron:
LPAALVDPQ
Uniprot ID:
Q6ZQT7
Source protein:
Putative uncharacterized protein FLJ44672
Source gene:
-
Class:
DEG_SIAH_1
Location:
66:74
E3 ligase:
SIAH1,SIAH2,SIAH3
DEGRON score:
0.8708
ASA_SCORE:
64.1222
COIL:
0.7412
CONS_SCORE:
0
DSS_SCORE:
0.5745
HELIX:
0.2111
FCONS_SCORE:
0
RIG_SCORE:
0.7354
Degron related mutations and impact score
Mutation
Sample
Cancer
Dataset
Degron
Degron class
Impact score
Drug responses associated with - mutations
Sample
Cancer
Mutation (In Degron?)
Dataset
Drug
IC50
All proteins holding degron of LPAALVDPQ
Uniprot ID
Source protein
Degron class
Location
Hit
E3 ligase
Degron score
Detail
Q6ZQT7
Putative uncharacterized protein FLJ44672
DEG_SIAH_1
66:74
LPAALVDPQ
SIAH1,SIAH2,SIAH3
0.8708
More...