DegronMD

Uniprot ID: Q8WW14

Source protein: Uncharacterized protein C10orf82

Source gene: C10orf82

Class: DEG_SCF_FBW7_1

Location: 11:18

E3 ligase: FBXW7

DEGRON score: 0.8388

ASA_SCORE: 45.6875

COIL: 0.8719

CONS_SCORE: 0.7973

DSS_SCORE: 0.2494

HELIX: 0.0214

FCONS_SCORE: 1.2023

RIG_SCORE: 0.7339

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.L24I	TCGA-AX-A3G9	UCEC	TCGA	LPITPGYS	DEG_SCF_FBW7_1	0.1667
p.L24I	DO41241	UCEC	ICGC	LPITPGYS	DEG_SCF_FBW7_1	0.1667
p.F7L	DO228978	LICA	ICGC	LPITPGYS	DEG_SCF_FBW7_1	0.2222
p.S18R	DO229035	LICA	ICGC	LPITPGYS	DEG_SCF_FBW7_1	0.7427
p.P12T	DO229037	LICA	ICGC	LPITPGYS	DEG_SCF_FBW7_1	0.5919
p.L24R	SIDM01126	Small Cell Lung Carcinoma	GDSC	LPITPGYS	DEG_SCF_FBW7_1	0.1667
p.L24R	SIDM00690	Head and Neck Carcinoma	GDSC	LPITPGYS	DEG_SCF_FBW7_1	0.1667

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q8WW14	Uncharacterized protein C10orf82	DEG_SCF_FBW7_1	11:18	LPITPGYS	FBXW7	0.8388	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons