DegronMD

Uniprot ID: Q9ULJ1

Source protein: Protein BCAP

Source gene: ODF2L

Class: LIG_APCC_ABBA_1

Location: 68:73

E3 ligase: APC,CDC20,FZR1

DEGRON score: 0.7135

ASA_SCORE: 80.0833

COIL: 0.048

CONS_SCORE: 0.4939

DSS_SCORE: 0.0424

HELIX: 0.952

FCONS_SCORE: 1.2516

RIG_SCORE: 0.8992

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.E81Q	TCGA-AC-A23H	BRCA	TCGA	LPLFKD	LIG_APCC_ABBA_1	0.1111
p.E81Q	DO2401	BRCA	ICGC	LPLFKD	LIG_APCC_ABBA_1	0.1111
p.E58K	TCGA-AX-A06F	UCEC	TCGA	LPLFKD	LIG_APCC_ABBA_1	0.0556
p.E58K	TCGA-AX-A0J0	UCEC	TCGA	LPLFKD	LIG_APCC_ABBA_1	0.0556
p.E58K	DO48701	LIRI	ICGC	LPLFKD	LIG_APCC_ABBA_1	0.0556
p.E58K	DO41752	UCEC	ICGC	LPLFKD	LIG_APCC_ABBA_1	0.0556
p.E58K	DO41133	UCEC	ICGC	LPLFKD	LIG_APCC_ABBA_1	0.0556
p.I59V	DO231622	LINC	ICGC	LPLFKD	LIG_APCC_ABBA_1	0.0833
p.I60L	DO231070	LUSC	ICGC	LPLFKD	LIG_APCC_ABBA_1	0.1111
p.L66F	SIDM00543	Melanoma	GDSC	LPLFKD	LIG_APCC_ABBA_1	0.2778

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q9ULJ1	Protein BCAP	LIG_APCC_ABBA_1	68:73	LPLFKD	APC,CDC20,FZR1	0.7135	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons