DegronMD: protein-targeted degradation, mutation and drug response to degrons
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Degron:
LPPAFVDPE
Uniprot ID:
Q6ZRM9
Source protein:
Putative uncharacterized protein FLJ46235
Source gene:
-
Class:
DEG_SIAH_1
Location:
49:57
E3 ligase:
SIAH1,SIAH2,SIAH3
DEGRON score:
0.9903
ASA_SCORE:
60.6667
COIL:
0.8213
CONS_SCORE:
0.4726
DSS_SCORE:
0.4305
HELIX:
0.1161
FCONS_SCORE:
1.061
RIG_SCORE:
0.7214
Degron related mutations and impact score
Mutation
Sample
Cancer
Dataset
Degron
Degron class
Impact score
Drug responses associated with - mutations
Sample
Cancer
Mutation (In Degron?)
Dataset
Drug
IC50
All proteins holding degron of LPPAFVDPE
Uniprot ID
Source protein
Degron class
Location
Hit
E3 ligase
Degron score
Detail
Q6ZRM9
Putative uncharacterized protein FLJ46235
DEG_SIAH_1
49:57
LPPAFVDPE
SIAH1,SIAH2,SIAH3
0.9903
More...