DegronMD: protein-targeted degradation, mutation and drug response to degrons
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BSML
CPH
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Degron:
LQCGRGVPR
Uniprot ID:
Q8N2X6
Source protein:
Uncharacterized protein EXOC3-AS1
Source gene:
EXOC3-AS1
Class:
SCF_FBXL2
Location:
13:21
E3 ligase:
FBXL2
DEGRON score:
0.5622
ASA_SCORE:
62.9222
COIL:
0.735
CONS_SCORE:
0.8888
DSS_SCORE:
0.3825
HELIX:
0.2054
FCONS_SCORE:
1.0292
RIG_SCORE:
0.6952
Degron related mutations and impact score
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Drug responses associated with EXOC3-AS1 mutations
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All proteins holding degron of LQCGRGVPR
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Uniprot ID
Source protein
Degron class
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E3 ligase
Degron score
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Q8N2X6
Uncharacterized protein EXOC3-AS1
SCF_FBXL2
13:21
LQCGRGVPR
FBXL2
0.5622
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