DegronMD: protein-targeted degradation, mutation and drug response to degrons
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Degron:
LQITPPIS
Uniprot ID:
Q6ICC9
Source protein:
Retrotransposon Gag-like protein 6
Source gene:
RTL6
Class:
DEG_SCF_FBW7_1
Location:
77:84
E3 ligase:
FBXW7
DEGRON score:
0.972
ASA_SCORE:
94.55
COIL:
0.9536
CONS_SCORE:
0.9936
DSS_SCORE:
0.517
HELIX:
0.0194
FCONS_SCORE:
1.0006
RIG_SCORE:
0.7213
Degron related mutations and impact score
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Drug responses associated with RTL6 mutations
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All proteins holding degron of LQITPPIS
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Uniprot ID
Source protein
Degron class
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E3 ligase
Degron score
Detail
Q6ICC9
Retrotransposon Gag-like protein 6
DEG_SCF_FBW7_1
77:84
LQITPPIS
FBXW7
0.972
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