DegronMD: protein-targeted degradation, mutation and drug response to degrons
Home
(current)
Browse
Proteins/Degrons
Mutations
Drug response
Network-rewiring
Drug resistance
Search
Tutorial
Download
Contact
Links
BSML
CPH
CGC
Degron:
LRKELERVA
Uniprot ID:
P0CJ92
Source protein:
Golgin subfamily A member 8H
Source gene:
GOLGA8H
Class:
DEG_APCC_DBOX_1
Location:
311:319
E3 ligase:
APC,CDC20,FZR1
DEGRON score:
0.5933
ASA_SCORE:
103.5
COIL:
0.0732
CONS_SCORE:
0.9334
DSS_SCORE:
0.4201
HELIX:
0.9301
FCONS_SCORE:
1.1618
RIG_SCORE:
0.7632
Degron related mutations and impact score
Mutation
Sample
Cancer
Dataset
Degron
Degron class
Impact score
Drug responses associated with GOLGA8H mutations
Sample
Cancer
Mutation (In Degron?)
Dataset
Drug
IC50
All proteins holding degron of LRKELERVA
Uniprot ID
Source protein
Degron class
Location
Hit
E3 ligase
Degron score
Detail
P0CJ92
Golgin subfamily A member 8H
DEG_APCC_DBOX_1
311:319
LRKELERVA
APC,CDC20,FZR1
0.5933
More...