DegronMD: protein-targeted degradation, mutation and drug response to degrons
Home
(current)
Browse
Proteins/Degrons
Mutations
Drug response
Network-rewiring
Drug resistance
Search
Tutorial
Download
Contact
Links
BSML
CPH
CGC
Degron:
LRQQLDDVH
Uniprot ID:
Q8IYA2
Source protein:
Putative coiled-coil domain-containing protein 144C
Source gene:
CCDC144CP
Class:
DEG_APCC_DBOX_1
Location:
862:870
E3 ligase:
APC,CDC20,FZR1
DEGRON score:
0.5077
ASA_SCORE:
95.2
COIL:
0.0342
CONS_SCORE:
0.7342
DSS_SCORE:
0.4722
HELIX:
0.9664
FCONS_SCORE:
1.1667
RIG_SCORE:
0.7686
Degron related mutations and impact score
Mutation
Sample
Cancer
Dataset
Degron
Degron class
Impact score
Drug responses associated with CCDC144CP mutations
Sample
Cancer
Mutation (In Degron?)
Dataset
Drug
IC50
All proteins holding degron of LRQQLDDVH
Uniprot ID
Source protein
Degron class
Location
Hit
E3 ligase
Degron score
Detail
Q8IYA2
Putative coiled-coil domain-containing protein 144C
DEG_APCC_DBOX_1
862:870
LRQQLDDVH
APC,CDC20,FZR1
0.5077
More...