DegronMD

Uniprot ID: Q5T0D9

Source protein: Tumor protein p63-regulated gene 1-like protein

Source gene: TPRG1L

Class: DEG_APCC_DBOX_1

Location: 42:50

E3 ligase: APC,CDC20,FZR1

DEGRON score: 0.9639

ASA_SCORE: 92.5667

COIL: 0.8368

CONS_SCORE: 0.3801

DSS_SCORE: 0.5295

HELIX: 0.075

FCONS_SCORE: 1.0644

RIG_SCORE: 0.7852

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.I51L	ACH-000307	Pancreatic Cancer	CCLE	LRQTLWPLS	DEG_APCC_DBOX_1	0.3056
p.I51L	ACH-000372	Leukemia	CCLE	LRQTLWPLS	DEG_APCC_DBOX_1	0.3056
p.I51L	ACH-000471	Liver Cancer	CCLE	LRQTLWPLS	DEG_APCC_DBOX_1	0.3056
p.R35L	ACH-000844	Lung Cancer	CCLE	LRQTLWPLS	DEG_APCC_DBOX_1	0.1389

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q5T0D9	Tumor protein p63-regulated gene 1-like protein	DEG_APCC_DBOX_1	42:50	LRQTLWPLS	APC,CDC20,FZR1	0.9639	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons