DegronMD: protein-targeted degradation, mutation and drug response to degrons
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BSML
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Degron:
LRRTPPRT
Uniprot ID:
A8MUU9
Source protein:
Putative uncharacterized protein ENSP00000383309
Source gene:
-
Class:
DEG_SCF_FBW7_1
Location:
453:460
E3 ligase:
FBXW7
DEGRON score:
0.9617
ASA_SCORE:
114.275
COIL:
0.9706
CONS_SCORE:
0.3364
DSS_SCORE:
0.7722
HELIX:
0.0123
FCONS_SCORE:
0.8584
RIG_SCORE:
0.6917
Degron related mutations and impact score
Mutation
Sample
Cancer
Dataset
Degron
Degron class
Impact score
Drug responses associated with - mutations
Sample
Cancer
Mutation (In Degron?)
Dataset
Drug
IC50
All proteins holding degron of LRRTPPRT
Uniprot ID
Source protein
Degron class
Location
Hit
E3 ligase
Degron score
Detail
A8MUU9
Putative uncharacterized protein ENSP00000383309
DEG_SCF_FBW7_1
453:460
LRRTPPRT
FBXW7
0.9617
More...