DegronMD

Uniprot ID: Q7Z7M1

Source protein: Adhesion G-protein coupled receptor D2

Source gene: ADGRD2

Class: DEG_APCC_DBOX_1

Location: 133:141

E3 ligase: APC,CDC20,FZR1

DEGRON score: 0.9312

ASA_SCORE: 67.2333

COIL: 0.7422

CONS_SCORE: 0.5527

DSS_SCORE: 0.268

HELIX: 0.1071

FCONS_SCORE: 0.9993

RIG_SCORE: 0.778

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.V131M	SIDM00214	Colorectal Carcinoma	GDSC	LRSPLPELA	DEG_APCC_DBOX_1	0.2778
p.D134H	SIDM01072	Squamous Cell Lung Carcinoma	GDSC	LRSPLPELA	DEG_APCC_DBOX_1	0.7688

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q7Z7M1	Adhesion G-protein coupled receptor D2	DEG_APCC_DBOX_1	133:141	LRSPLPELA	APC,CDC20,FZR1	0.9312	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons