DegronMD: protein-targeted degradation, mutation and drug response to degrons
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Degron:
LRTQLPDVG
Uniprot ID:
A6NNH2
Source protein:
Protein FAM90A27P
Source gene:
FAM90A27P
Class:
DEG_APCC_DBOX_1
Location:
312:320
E3 ligase:
APC,CDC20,FZR1
DEGRON score:
0.7769
ASA_SCORE:
87.0667
COIL:
0.8196
CONS_SCORE:
0.0952
DSS_SCORE:
0.5621
HELIX:
0.1022
FCONS_SCORE:
0.301
RIG_SCORE:
0.7416
Degron related mutations and impact score
Mutation
Sample
Cancer
Dataset
Degron
Degron class
Impact score
Drug responses associated with FAM90A27P mutations
Sample
Cancer
Mutation (In Degron?)
Dataset
Drug
IC50
All proteins holding degron of LRTQLPDVG
Uniprot ID
Source protein
Degron class
Location
Hit
E3 ligase
Degron score
Detail
A6NNH2
Protein FAM90A27P
DEG_APCC_DBOX_1
312:320
LRTQLPDVG
APC,CDC20,FZR1
0.7769
More...