DegronMD: protein-targeted degradation, mutation and drug response to degrons
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Degron:
LTPTLS
Uniprot ID:
Q6XXX2
Source protein:
Putative uncharacterized protein encoded by LINC00114
Source gene:
LINC00114
Class:
DEG_SCF_FBW7_1
Location:
69:74
E3 ligase:
FBXW7
DEGRON score:
0.9521
ASA_SCORE:
60.35
COIL:
0.7272
CONS_SCORE:
0
DSS_SCORE:
0.5577
HELIX:
0.1373
FCONS_SCORE:
0
RIG_SCORE:
0.6759
Degron related mutations and impact score
Mutation
Sample
Cancer
Dataset
Degron
Degron class
Impact score
Drug responses associated with LINC00114 mutations
Sample
Cancer
Mutation (In Degron?)
Dataset
Drug
IC50
All proteins holding degron of LTPTLS
Uniprot ID
Source protein
Degron class
Location
Hit
E3 ligase
Degron score
Detail
Q6XXX2
Putative uncharacterized protein encoded by LINC00114
DEG_SCF_FBW7_1
69:74
LTPTLS
FBXW7
0.9521
More...