DegronMD: protein-targeted degradation, mutation and drug response to degrons
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Degron:
LTPVLT
Uniprot ID:
P59797
Source protein:
Selenoprotein V
Source gene:
SELENOV
Class:
DEG_SCF_FBW7_1
Location:
46:51
E3 ligase:
FBXW7
DEGRON score:
0.9602
ASA_SCORE:
98.7167
COIL:
0.9657
CONS_SCORE:
0.4547
DSS_SCORE:
0.6338
HELIX:
0.0082
FCONS_SCORE:
0.94
RIG_SCORE:
0.7385
Degron related mutations and impact score
Mutation
Sample
Cancer
Dataset
Degron
Degron class
Impact score
Drug responses associated with SELENOV mutations
Sample
Cancer
Mutation (In Degron?)
Dataset
Drug
IC50
All proteins holding degron of LTPVLT
Uniprot ID
Source protein
Degron class
Location
Hit
E3 ligase
Degron score
Detail
P59797
Selenoprotein V
DEG_SCF_FBW7_1
46:51
LTPVLT
FBXW7
0.9602
More...