DegronMD: protein-targeted degradation, mutation and drug response to degrons
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BSML
CPH
CGC
Degron:
LTRTPPGT
Uniprot ID:
A8MUU9
Source protein:
Putative uncharacterized protein ENSP00000383309
Source gene:
-
Class:
DEG_SCF_FBW7_1
Location:
444:451
E3 ligase:
FBXW7
DEGRON score:
0.9401
ASA_SCORE:
88.275
COIL:
0.9508
CONS_SCORE:
0.3997
DSS_SCORE:
0.7592
HELIX:
0.0194
FCONS_SCORE:
1.0617
RIG_SCORE:
0.6295
Degron related mutations and impact score
Mutation
Sample
Cancer
Dataset
Degron
Degron class
Impact score
Drug responses associated with - mutations
Sample
Cancer
Mutation (In Degron?)
Dataset
Drug
IC50
All proteins holding degron of LTRTPPGT
Uniprot ID
Source protein
Degron class
Location
Hit
E3 ligase
Degron score
Detail
A8MUU9
Putative uncharacterized protein ENSP00000383309
DEG_SCF_FBW7_1
444:451
LTRTPPGT
FBXW7
0.9401
More...