Degron: LWETPDVS
2-
DPH2
404:411
FBXW7
0.9568
69.4
0.6125
0.3763
0.5006
0.1685
1.3055
0.7839
Degron related mutations and impact score
Mutation |
Sample |
Cancer |
Dataset |
Degron |
Degron class |
Impact score |
p.L397P | TCGA-BR-8078 | STAD | TCGA | LWETPDVS | DEG_SCF_FBW7_1 | 0.1389 |
p.E406K | TCGA-D5-6531 | COAD | TCGA | LWETPDVS | DEG_SCF_FBW7_1 | 0.591 |
Drug responses associated with DPH2 mutations
Sample |
Cancer |
Mutation (In Degron?) |
Dataset |
Drug |
IC50 |
All proteins holding degron of LWETPDVS
Uniprot ID |
Source protein |
Degron class |
Location |
Hit |
E3 ligase |
Degron score |
Detail |
Q9BQC3 | 2- | DEG_SCF_FBW7_1 | 404:411 | LWETPDVS | FBXW7 | 0.9568 | More... |