DegronMD: protein-targeted degradation, mutation and drug response to degrons
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Degron:
LYPFQD
Uniprot ID:
A6NHS1
Source protein:
Putative uncharacterized protein ENSP00000347057
Source gene:
-
Class:
LIG_APCC_ABBA_1
Location:
58:63
E3 ligase:
APC,CDC20,FZR1
DEGRON score:
0.9953
ASA_SCORE:
67.95
COIL:
0.779
CONS_SCORE:
0
DSS_SCORE:
0.6004
HELIX:
0.1208
FCONS_SCORE:
0
RIG_SCORE:
0.7204
Degron related mutations and impact score
Mutation
Sample
Cancer
Dataset
Degron
Degron class
Impact score
Drug responses associated with - mutations
Sample
Cancer
Mutation (In Degron?)
Dataset
Drug
IC50
All proteins holding degron of LYPFQD
Uniprot ID
Source protein
Degron class
Location
Hit
E3 ligase
Degron score
Detail
A6NHS1
Putative uncharacterized protein ENSP00000347057
LIG_APCC_ABBA_1
58:63
LYPFQD
APC,CDC20,FZR1
0.9953
More...