DegronMD

Uniprot ID: P58549

Source protein: FXYD domain-containing ion transport regulator 7

Source gene: FXYD7

Class: DEG_SCF_FBW7_1

Location: 1:7

E3 ligase: FBXW7

DEGRON score: 0.6336

ASA_SCORE: 99.4571

COIL: 0.9714

CONS_SCORE: 0.6152

DSS_SCORE: 0.9339

HELIX: 0.0099

FCONS_SCORE: 0.7965

RIG_SCORE: 0.6662

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.P12S	TCGA-TN-A7HJ	HNSC	TCGA	MATPTQT	DEG_SCF_FBW7_1	0.1944
p.P12S	DO219077	HNSC	ICGC	MATPTQT	DEG_SCF_FBW7_1	0.1944
p.E13G	DO228882	MALY	ICGC	MATPTQT	DEG_SCF_FBW7_1	0.1667
p.P12A	ACH-002396	Bone Cancer	CCLE	MATPTQT	DEG_SCF_FBW7_1	0.1944
p.P12A	Sarc9371	bone	COSMIC	MATPTQT	DEG_SCF_FBW7_1	0.1944

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
P58549	FXYD domain-containing ion transport regulator 7	DEG_SCF_FBW7_1	1:7	MATPTQT	FBXW7	0.6336	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons