DegronMD: protein-targeted degradation, mutation and drug response to degrons
Home
(current)
Browse
Proteins/Degrons
Mutations
Drug response
Network-rewiring
Drug resistance
Search
Tutorial
Download
Contact
Links
BSML
CPH
CGC
Degron:
MIR
Uniprot ID:
P30711
Source protein:
Glutathione S-transferase theta-1
Source gene:
GSTT1
Class:
DEG_APCC_TPR_1
Location:
238:240
E3 ligase:
APC,CDC20,FZR1
DEGRON score:
0.652
ASA_SCORE:
106.2333
COIL:
0.766
CONS_SCORE:
0.329
DSS_SCORE:
0.6084
HELIX:
0.2287
FCONS_SCORE:
0.9765
RIG_SCORE:
0.8786
Degron related mutations and impact score
Mutation
Sample
Cancer
Dataset
Degron
Degron class
Impact score
p.M232I
DO33688
PACA
ICGC
MIR
DEG_APCC_TPR_1
0.1667
Drug responses associated with GSTT1 mutations
Sample
Cancer
Mutation (In Degron?)
Dataset
Drug
IC50
All proteins holding degron of MIR
Uniprot ID
Source protein
Degron class
Location
Hit
E3 ligase
Degron score
Detail
P30711
Glutathione S-transferase theta-1
DEG_APCC_TPR_1
238:240
MIR
APC,CDC20,FZR1
0.652
More...