DegronMD: protein-targeted degradation, mutation and drug response to degrons
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BSML
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Degron:
MQTTPQES
Uniprot ID:
I3L273
Source protein:
Golgi-associated olfactory signaling regulator
Source gene:
GFY
Class:
DEG_SCF_FBW7_1
Location:
174:181
E3 ligase:
FBXW7
DEGRON score:
0.831
ASA_SCORE:
102.5125
COIL:
0.9676
CONS_SCORE:
0
DSS_SCORE:
0.8176
HELIX:
0.0135
FCONS_SCORE:
0
RIG_SCORE:
0.6836
Degron related mutations and impact score
Mutation
Sample
Cancer
Dataset
Degron
Degron class
Impact score
Drug responses associated with GFY mutations
Sample
Cancer
Mutation (In Degron?)
Dataset
Drug
IC50
All proteins holding degron of MQTTPQES
Uniprot ID
Source protein
Degron class
Location
Hit
E3 ligase
Degron score
Detail
I3L273
Golgi-associated olfactory signaling regulator
DEG_SCF_FBW7_1
174:181
MQTTPQES
FBXW7
0.831
More...