DegronMD: protein-targeted degradation, mutation and drug response to degrons
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Degron:
MTPCLE
Uniprot ID:
Q52M75
Source protein:
Putative uncharacterized protein encoded by LINC01554
Source gene:
LINC01554
Class:
DEG_SCF_FBW7_2
Location:
1:6
E3 ligase:
FBXW7
DEGRON score:
0.6146
ASA_SCORE:
75.2667
COIL:
0.4783
CONS_SCORE:
1
DSS_SCORE:
0.5432
HELIX:
0.5085
FCONS_SCORE:
1
RIG_SCORE:
0.8078
Degron related mutations and impact score
Mutation
Sample
Cancer
Dataset
Degron
Degron class
Impact score
Drug responses associated with LINC01554 mutations
Sample
Cancer
Mutation (In Degron?)
Dataset
Drug
IC50
All proteins holding degron of MTPCLE
Uniprot ID
Source protein
Degron class
Location
Hit
E3 ligase
Degron score
Detail
Q52M75
Putative uncharacterized protein encoded by LINC01554
DEG_SCF_FBW7_2
1:6
MTPCLE
FBXW7
0.6146
More...