DegronMD

Uniprot ID: P98088

Source protein: Mucin-5AC

Source gene: MUC5AC

Class: DEG_SCF_FBW7_1

Location: 1849:1856

E3 ligase: FBXW7

DEGRON score: 0.9849

ASA_SCORE: 81.6

COIL: 0.8754

CONS_SCORE: 0.3491

DSS_SCORE: 0.5091

HELIX: 0.0156

FCONS_SCORE: 1.3095

RIG_SCORE: 0.6102

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.E1842V	SIDM00507	Other Solid Cancers	GDSC	MTSTPGST	DEG_SCF_FBW7_1	0.1389
p.P1860Q	SIDM00013	Melanoma	GDSC	MTSTPGST	DEG_SCF_FBW7_1	0.2222
p.S1858N	SIDM00364	B-Lymphoblastic Leukemia	GDSC	MTSTPGST	DEG_SCF_FBW7_1	0.2778

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
P98088	Mucin-5AC	DEG_SCF_FBW7_1	1849:1856	MTSTPGST	FBXW7	0.9849	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons