DegronMD

Uniprot ID: Q7L775

Source protein: EPM2A-interacting protein 1

Source gene: EPM2AIP1

Class: DEG_SCF_FBW7_1

Location: 1:8

E3 ligase: FBXW7

DEGRON score: 0.8485

ASA_SCORE: 129.8875

COIL: 0.9315

CONS_SCORE: 0.96

DSS_SCORE: 0.6536

HELIX: 0.0256

FCONS_SCORE: 1.1596

RIG_SCORE: 0.7835

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.R7I	SIDM01588	Endometrial Carcinoma	GDSC	MWMTPKRS	DEG_SCF_FBW7_1	0.6991
p.R7I	ACH-000993	Endometrial/Uterine Cancer	CCLE	MWMTPKRS	DEG_SCF_FBW7_1	0.6991
p.M3V	ACH-001656	Leukemia	CCLE	MWMTPKRS	DEG_SCF_FBW7_1	0.6097

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q7L775	EPM2A-interacting protein 1	DEG_SCF_FBW7_1	1:8	MWMTPKRS	FBXW7	0.8485	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons