DegronMD

Degron: NAADSYSWVP

Uniprot ID: Q9NPY3

Source protein: Complement component C1q receptor

Source gene: CD93

Class: CBL_PTK

Location: 623:632

E3 ligase: CBL

DEGRON score: 0.7458

ASA_SCORE: 32.22

COIL: 0.5622

CONS_SCORE: 0.5079

DSS_SCORE: 0.5687

HELIX: 0.1716

FCONS_SCORE: 1.1149

RIG_SCORE: 0.7004

Degron related mutations and impact score

Show entries

Search:

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.S629F	TCGA-EB-A24D	SKCM	TCGA	NAADSYSWVP	CBL_PTK	0.9093
p.S629F	TCGA-L5-A8NM	ESCA	TCGA	NAADSYSWVP	CBL_PTK	0.9093
p.S629F	DO222837	MELA	ICGC	NAADSYSWVP	CBL_PTK	0.9093
p.S629F	DO37440	SKCM	ICGC	NAADSYSWVP	CBL_PTK	0.9093
p.P632L	TCGA-EE-A2MF	SKCM	TCGA	NAADSYSWVP	CBL_PTK	0.7582
p.P632L	DO222491	MELA	ICGC	NAADSYSWVP	CBL_PTK	0.7582
p.P632L	DO51249	SKCM	ICGC	NAADSYSWVP	CBL_PTK	0.7582
p.S627N	SIDM00224	Mesothelioma	GDSC	NAADSYSWVP	CBL_PTK	0.7069
p.S627N	IST-MES1	pleura	COSMIC	NAADSYSWVP	CBL_PTK	0.7069
p.P632Q	DO231778	LINC	ICGC	NAADSYSWVP	CBL_PTK	0.7035
p.P632S	ACH-001567	Skin Cancer	CCLE	NAADSYSWVP	CBL_PTK	0.6752
p.S637C	SIDM01134	Small Cell Lung Carcinoma	GDSC	NAADSYSWVP	CBL_PTK	0.6389
p.S637C	ACH-000292	Lung Cancer	CCLE	NAADSYSWVP	CBL_PTK	0.6389
p.S637C	NCI-H841	lung	COSMIC	NAADSYSWVP	CBL_PTK	0.6389
p.A625T	TCGA-A6-2686	COAD	TCGA	NAADSYSWVP	CBL_PTK	0.6028
p.A625T	TCGA-HU-A4GT	STAD	TCGA	NAADSYSWVP	CBL_PTK	0.6028
p.A625T	DO7828	COAD	ICGC	NAADSYSWVP	CBL_PTK	0.6028
p.A625T	DO48020	STAD	ICGC	NAADSYSWVP	CBL_PTK	0.6028
p.A624V	TCGA-AA-3977	COAD	TCGA	NAADSYSWVP	CBL_PTK	0.5825
p.A624V	DO8730	COAD	ICGC	NAADSYSWVP	CBL_PTK	0.5825
p.A624V	DO33432	PACA	ICGC	NAADSYSWVP	CBL_PTK	0.5825
p.A624V	SIDM01943	Colorectal Carcinoma	GDSC	NAADSYSWVP	CBL_PTK	0.5825
p.R634Q	SIDM01768	Melanoma	GDSC	NAADSYSWVP	CBL_PTK	0.2778
p.R634Q	ACH-000899	Skin Cancer	CCLE	NAADSYSWVP	CBL_PTK	0.2778
p.E636G	TCGA-86-8074	LUAD	TCGA	NAADSYSWVP	CBL_PTK	0.2222

Showing 1 to 25 of 39 entries

Previous1 2Next

Drug responses associated with CD93 mutations

Show entries

Search:

Sample	Cancer	Mutation (In Degron?)	Dataset	Drug	IC50
No data available in table

Showing 0 to 0 of 0 entries

All proteins holding degron of NAADSYSWVP

Show entries

Search:

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q9NPY3	Complement component C1q receptor	CBL_PTK	623:632	NAADSYSWVP	CBL	0.7458	More...

Showing 1 to 1 of 1 entries